מידע ייעוץ והזמנה טלפונית - 09-8829992    בתי מרקחת בהם ניתן לרכוש Point4 (ראה סוף ש/ת)   

FAQ

What is Fatigue (asthenia)?

Fatigue/asthenia is the most common symptom described by patients with cancer with a prevalence ranging from 60% to more than 96%, and many persist after cure of cancer.  Perhaps no other symptom is more classically associated with cancer than fatigue. Furthermore fatigue is often cited as the most disruptive symptom of a patient's daily routine (5). The symptom accompanies surgery, chemotherapy, radiation therapy, and biologic response modifier therapy. Chemotherapy- and radiation-therapy-related fatigue may be associated with anemia or with an accumulation of cell destruction end products.[1,2] In the case of radiation therapy, fatigue may be caused by increased energy requirements to repair damaged epithelial tissue.[3

Although the exact mechanism of fatigue in patients with cancer is often not known its causes are diverse.  A high frequency of fatigue is reported after different treatments, including surgery, chemotherapy, and bone marrow transplantation. Chemotherapy has been reported to cause fatigue in 75% to 100% of cases, with the symptoms persisting months to years after the treatment is completed. Although radiation therapy is a localized treatment, the incidence of fatigue with its use runs high, especially with abdominal radiation.

Fatigue increases during radiation therapy and can endure for many months after the treatment is completed. In addition numerous factors related to the moods, beliefs, attitudes, and reactions to stressors of people with cancer are thought to contribute to the development of chronic fatigue.(4)

Adrenal insufficiency in critically ill patients were the corticotropic axis is greatly activated causing cortisol concentration that correlates with illness-severity and are highest in individuals with highest mortality (7).is also a major Fatigue (lack of energy, stamina, gastric pain, weight loss, nausea, vomiting, dizziness….) inducing factor that should be addressed when coming to treat it. (7)

Because the etiology of cancer related fatigue is generally multifactoral the pharmaceutical management should, whenever possible, be directed toward etiology.(5)

How is it treated?

"Although a variety of treatment-and disease-related factors may contribute to the development of fatigue,  the biochemical, physiologic, psychologic, and behavioral mechanisms of this symptom complex are poorly understood" "There is no standard of care for the assessment or treatment of fatigue in patients with cancer".* (citations from US  National Cancer Institute - Fatigue PDQ for Professionals) 

What is the effective mechanism of Point4™?

Health is dependent on the healthy functioning of cells    Stress, physical or emotional, has an impact at the cellular level - depriving cells of their energy supply. When a cell cannot function properly it becomes weak and damaged. The body gradually breaks down and disease and aging processes begin. This is where adaptogens enter the picture in a remarkable way.        From the beginning they allow the cell to absorb and use its available energy by uniting glucose and enzymes. Adaptogens also prevent the formation of complex molecules which obstruct the cells from manufacturing energy properly. The body is allowed full access to its energy potential and the cells remain healthy.

This process actually takes place in every cell in the body. The cells return to healthier functioning as the various body organs and systems begin to normalize. This normalizing effect may be noticeable in various internal or external ways. Ultimately, the entire body will normalize itself and achieve the balance that nature intended.

For whom are the product meant?

Point4Life™ is recommend  for every persons who is before, undergoing or after chemo or radiotherapy, marrow transplantation, recovering from surgery or major illness.

Point4Energy™ is recommended for every person living a stressful life, physical or emotional, exposed to harmful substances or environments as well as for athletes and individuals engaged in extreme activities.

What is the rational behind Point4Life™

Point4Life™ development is based on the well researched and documented thesis that non-specific-stress is playing a dominant role in cancer related fatigue and may contribute to cancer development  and that Point4Life™'s ingredients, may exaggerate an already existing biphasic response to stress via inhibition of enzymes which limit the binding of stress hormones to their receptors and by thus protect body from their harmful effects.

What are the indications ?

Point4Life™ is to be used as an adjuvant complementary therapy to surgical, chemo and radiation therapies, and following marrow transplantation. Point4Life™is expected to increase body's nonspecific resistance to physical and mental stressors, protect body from harmful effects at cellular level and by thus to minimize fatigue symptoms generally associated with cancer and critical illnesses i.e. lack of energy, stamina, gastric pain, weight loss, nausea, vomiting, dizziness…

 "Post-treatment" - Due to its "homeostasis regulatory" (biphasic response to stress  attributes, Point4Life™ is expected to play a significant role in the convalescence of cancer and critically ill patients by "protection" against fatigue persistence as well as reoccurrence or development of cancer.

Which factors are answered by Point4Life™ ?

Point4Life™ is designed to answer to a dominant   etiological factors namely: The regulation of "non-specific-stress" harmful  effects on the body's homeostatic mechanism.

What is the effective mechanism of Point4™ ?

The probable biphasic effect results from increased occupancy of positive and negative feedback stress hormone receptors by their natural ligands due to inhibition of specific enzymes which function to limit receptor occupancy. Specially is suggested that PG ( inhibits 11-beta hydroxysteroid dehydrogenase one and ES  inhibits catechol-O-methyl transferase, both of which reside in close proximity to stress hormone  receptors and catalyze the degradation of stress hormones into inactive compounds.  In addition it is suggested that the increased energy said to result from PG and may be a consequence of their increasing the occupancy of stress hormone receptors which function to redistribute the body's energy reserves from regeneration to activity. 

What does Point4™ consist of?

Point4™ consists of Adaptogens (unique phyto-chemicals), anti-oxidants and vitamins.

Is Point4™ safe?

Adaptogens and their health beneficial effects have  been researched for over fifty years. The actual absorption of adaptogens, as all plant sterols, into  the human body is considerably minor. No side- effects have been detected.

In any case of an extremely rare disease, as well as during any medical treatment you should consult your doctor.

How much do you have to consume in order to       feel better?

An adequate amount of Point4Life™ is about  500mg      This amount is delivered in 1 capsule a day.

An adequate amount of Point4Energy™ is about 250mg  This amount is delivered in 1 capsule a day.

Does one  need an authority approval to market      Point4™?

Yes. Products containing plant sterols have to be approved by the appropriate regulatory authorities before they can be launched on the market.

Why are adaptogens and antioxidants essential    to human health?

When under stress, the body reacts by producing adrenaline which puts the whole body on a state of alert. The metabolism, blood pressure and circulation are disrupted; immunity and resistance are drastically reduced; performance suffers. In short, stress undermines health and destroys well-being.                                                                                               Oxidation of human cells appears to play a critical role in processes of aging and many degenerative diseases. Oxidation is caused by free radicals that are generated by body functions and lifestyle. Antioxidants can decrease oxidation by neutralizing free radicals. This can result in a slower aging process.

Point4™ antioxidants are  free radical scavengers and they are effective in the aqueous parts of human body. It can possibly recycle vitamin E. In practice this means that it enhances the effect of vitamin E also present in Point4™.

How  Adaptogens work at the Cellular Level?

Health is dependent on the healthy functioning of cells Stress, physical or emotional, has an impact at the cellular level - depriving cells of  their  energy supply. When a cell cannot function properly it becomes weak and damaged. The body gradually breaks down and disease and aging processes begin. This is where adaptogens enter the picture in a remarkable way. From the  beginning they allow the cell to absorb and use its available energy by uniting glucose and enzymes.

 Adaptogens also prevent the formation of  complex molecules which obstruct the cells  from manufacturing energy properly. The body  is  allowed full access to its energy potential and the ells remain healthy.

This process actually takes place in every cell in the body. The cells return to healthier functioning as the various body organs and systems begin to   normalize. This normalizing effect may be noticeable in various internal or external ways. Ultimately,   the entire body will normalize itself and achieve the balance that nature intended.

Is there anything else in nature which works this way?

No, Adaptogens are completely unique in nature. Scientists have struggled with stress for decades, but have never achieved this scientific breakthrough. Adaptogens are the only natural substances which can help the body protect itself form stress. They provide benefits which are impossible to get in any other way.

What does Point4™  do?

Point4™ cannot remove stress from anyone's life, but it helps the body adapt to stress. If you have been taking Point4™   the stress reaction is different. The response is sharper, but the production of adrenaline slows down and there is more left in reserve. One is not as quickly exhausted - fewer hormones are needed to achieve the same effect.

How Long Does Point4™ take to work?

From the moment you first take Point4™ it begins its work at the cellular level. The body limits its own reaction to stress, and cells return to a healthy state. This effect happens for everyone. Many of the internal changes are not felt - but they are both immediate and dramatic. The way these show up in everyday life may be subtle at first - but once the cellular changes happen, people can begin to see or feel the difference in themselves as the body adapts and balances itself. Within a few hours or a few weeks, each individual will ultimately experience Point4™'s impact - as noticeable changes in daily life, emotional and physical health and a sense of overall well being.

What about side effect & contraindications?

No known side effects recorded.  

Contraindications:  Concomitant use with high  blood pressure, anticoagulants or other heart medication or immunosuppressants should be  monitored.  

Have a question? - Ask us!

 copa@bezeqint.net

רשימת בתי מרקחת - חלקית   

References: (brief)

1.  Glaspy J, Bukowski R, Steinberg D, et al.: Impact of therapy with epoetin alfa on clinical outcomes in patients with nonmyeloid malignancies during cancer chemotherapy in community oncology practice. Procrit Study Group. J Clin Oncol 15 (3): 1218-34, 1997. 

2. Cella D, Mo F, Peterman A: Anemia, fatigue,  and quality of life in people with cancer and HIV infection. [Abstract] Blood 88 (10 Suppl 1): A-571, 146a, 1996. 

3. Haylock PJ, Hart LK: Fatigue in patients receiving localized radiation. Cancer Nurs 2(6): 461-467, 1979. 

4. Reich SG: The tired patient: psychological versus organic causes. Hosp Med 22 (7): 142-154, 1986. 

5. Roger Waltzman: Chalenges of Treating Cancer-Related Fatigue. Oncology – Special Edition (4): 35-39, 2001

6. Lillberg K, Vercasalo PK, et al: Stressful life events and risk of breast cancer in 10,808 women: a cohort study. Am J Epidemol 2003 Mar 1:157(5):415-23

7. Wiebke Arlt, Bruno Allolio: Adrenal insufficiency. The Lancet 2003;361:1881-93